When will I see the results?

Some improvement is visible immediately, but the main collagen effect develops gradually over approximately three months.

What is the downtime?

There's very little downtime. You might experience slight swelling, bruising, tenderness, or itching, but these usually fade quickly. Applying ice can help speed up recovery.

How long do the effects last?

Biostimulation stimulates your body's collagen, with results lasting 18-24 months.

Is Biostimulation safe?

When performed by a trained medical professional, Biostimulation has a well-established safety profile. It is bio-compatible and fully resorbable.

Is Biostimulation a permanent filler?

Biostimulation is a semi-permanent filler that provides long-lasting results. Like hyaluronic acid fillers, it's eventually metabolised by the body, but this process takes longer.

What is Biostimulation best for?

Biostimulation is ideal for reversing facial ageing and tightening loose skin. It restores lost volume and stimulates collagen for immediate and lasting results.

Biostimulation by Leading Oculoplastic Surgeon

Biostimulation is a treatment designed to support dermal structure and collagen renewal. At Perfect Eyes, it is used only where there is a clear clinical rationale, such as post-surgical contour imbalance, scarring, or age-related soft tissue changes affecting the periocular or mid-face region.

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Before & After Biostimulation before and after, a patient of Dr Sabrina Shah-Desai

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Biostimulation

At a Glance

Duration: 30 Minutes
Driving: Immediately
Anaesthesia: Local
Hospital Stay: None
Exercise: After 1 Day
Final results: After 3 Months
Pre admission tests: None
Addresses: Sagging Jawline and Nasolabial Folds
Down time: 1-2 Days

Why choose this treatment

Advantages of Biostimulation Treatment

Collagen Stimulation

Biostimulation promotes collagen production to restore volume, smooth wrinkles, and enhance skin's elasticity for a youthful appearance.

Long-Lasting Effects

Biostimulation lasts 18-24 months, offering enduring results as it gradually metabolises.

Quick Results

Enjoy noticeable improvements and corrections immediately after your first Biostimulation treatment.

Precision in Use

Biostimulation is administered only by trained oculoplastic surgeons using ultrasound mapping or anatomical guidance where required, ensuring safe placement and predictable outcomes.

Treatment Summary

What is Biostimulation Filler?

Biostimulation is a collagen-stimulating dermal filler that provides both immediate volume restoration and long-term tissue support through natural collagen synthesis.

Watch: Biostimulation

How Does Biostimulation Filler Procedure Work?

Important Notes:

Results vary between individuals.
Any filler treatment carries potential risks, including swelling, tenderness, bruising, or delayed inflammatory reaction.
Patients are advised to undergo consultation and suitability assessment before treatment.

Biostimulation being injected during treatment

Biostimulation contains smooth polycaprolactone (PCL) microspheres suspended in a carboxymethylcellulose (CMC) gel carrier. The gel provides immediate volumisation, while the microspheres act as a biostimulant, encouraging natural collagen synthesis over several months.

After applying a local anaesthetic, Dr Sabrina Shah-Desai or a qualified member of her team administers precise injections into the targeted areas to restore contour and balance.

This procedure is performed in a sterile medical setting and typically lasts about 30 minutes.

Patients are reviewed post-procedure to assess collagen response and ensure safe outcomes.

Real Patient Results

Biostimulation Filler Before and After

See the Biostimulation before and after results below, achieved by Dr Sabrina. Disclaimer: your results may vary. Any specific claims or duration of results vary for each patient and are not guaranteed.

6 cases

Individual results vary. All photographs are of real patients treated by Dr Sabrina Shah-Desai and are published with consent.

Meet the Expert: Dr Sabrina Shah-Desai

Dr Sabrina Shah-Desai is the founder and Medical Director of Perfect Eyes Clinic. With over two decades of surgical and non-surgical experience, she is considered one of the safest, most experienced oculoplastic surgeons in the UK.

Her extensive training, combined with her caring and empathetic nature, makes her a natural choice for patients seeking the very best care. Dr Sabrina appears consistently in Tatlermagazine as one of the UK's “Best Eye Surgeons” and “Top Doctors” since 2019.

Learn About Dr Sabrina

Royal College of Surgeons of England - register of Board-Certified Cosmetic SurgeonsBest Aesthetic Doctor - Safety in Beauty 2023Consultant Surgeon of the YearBest Surgical Result - Aesthetic Awards 2021Tatler Best Eye Surgeon 2019-2026

Transparent pricing

Biostimulation Cost in London

Prices are a guide; your surgeon confirms the total during consultation.

Perioral smokers lines restoration from £600
Deep and Static Wrinkles from £650
Jawline Contouring from £900
Pan Facial Restoration (6ml) from £1,600

Important: all cosmetic procedures incur 20% VAT. Fees are estimates and will be confirmed after medical consultation.

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Patient Questions About Biostimulation

Frequently Asked Questions

The questions patients ask most often, answered by the clinic. If yours isn’t here, ask us directly - we would be delighted to help.

Some improvement is visible immediately, but the main collagen effect develops gradually over approximately three months.
There's very little downtime. You might experience slight swelling, bruising, tenderness, or itching, but these usually fade quickly. Applying ice can help speed up recovery.
Biostimulation stimulates your body's collagen, with results lasting 18-24 months.
When performed by a trained medical professional, Biostimulation has a well-established safety profile. It is bio-compatible and fully resorbable.
Biostimulation is a semi-permanent filler that provides long-lasting results. Like hyaluronic acid fillers, it's eventually metabolised by the body, but this process takes longer.
Biostimulation is ideal for reversing facial ageing and tightening loose skin. It restores lost volume and stimulates collagen for immediate and lasting results.

Call or email us today, we would be delighted to answer your questions.

Ask a Question or Book an Appointment

Patient stories

Rated five stars by patients across the globe

4.8out of 5 from 240+ Google reviews

Desi Stevens

“Simply the best dermatologist for skin care and eye surgery. She is a safe and skilled doctor who is highly experienced and will meet your needs, her approach is a soft and natural aesthetic. She listens and communicates clearly, professionally and in a kind and personable manner. I have been looked after by Dr Sabrina for many years have always been extremely happy with her advice, procedures and results. Highly recommend, she is a talented Dr you can trust.”

Kealey Hessey

“Dr Sabrina is the magic eye fairy. Only 10 days after my lower lid bleph and midface lift and nearly all bruising and swelling has gone. After a lot of research, I knew after my initial consultation with Dr Sabrina she was the one I trusted. Such a warm & kind woman. I am so pleased I put my Trust in Dr Shah. Immensely happy with the results and will be back to get my upper eyes done in the future. Thank you to the whole team.”

Jo Kirby

“I had been recommended Dr Sabrina by a medical colleague & am extremely glad I made the journey from Southampton to the Perfect Eye Clinic in London to discuss blepharoplasty. The team were all so friendly & very professional and most importantly, Dr Sabrina informed me that I had a bilateral eye ptosis. This explained a number of issues I was experiencing. I will definitely be booking to have a correction of bilateral eye ptosis and upper blepharoplasty. Can't recommend enough.”

Shirley Ford

“I am so very happy with my experiences at Perfect Eyes. Dr Sabrina is an absolute Star. Extremely talented, very personable I just couldn't be happier with my results and her overall professionalism. But a big part of my review is how lovely the support staff are too. Namely Safiya and Lisa who greet you with such warmness and respect. I highly recommend this clinic as I have done so with many friends.”

Radhika Rajan

“Top notch surgeon. Dr.Sabrina Shah is the best. Very meticulous and focused. Very experienced and very skillful. Supported by a great team, Irvana at the office is efficient and directs empathy as well towards nervous patients like myself . All in all a great experience.”

Tina Stonely

“Dr Sabrina is so so kind and thorough in really assessing and understanding my needs and explaining in detail what works and the pros on cons of each treatment. I trust her implicitly and know she is the best physician in the UK and trainer to physicians for all aesthetic treatments. I cannot recommend her enough. You will not be disappointed choosing Sabrina.”

Tanya Del Federico

“Perfect Eyes provides an exceptional experience from start to finish. The team is warm, professional and highly knowledgeable, and every aspect of the consultation feels thorough and personalised. Sabrina combines outstanding surgical expertise with a genuine commitment to achieving natural, elegant results, taking the time to explain every option and ensure patients feel completely at ease. The care, attention to detail and standard of service are second to none. I would highly recommend Perfect Eyes to anyone looking for expert oculoplastic and aesthetic care.”

Minda Wang

“I am so happy with my experience. The results look natural, and I feel like a fresher version of myself since having my Biostimulation treatment with Doctor Sabrina. The whole experience was comfortable and professional, and I felt supported and well cared for throughout. I would definitely recommend this treatment to anyone looking for a natural-looking boost.”

Samantha Andrews

“Amazing. I’m so happy with the results. Sabrina is a master. She also has a wonderful bedside manner. I can’t recommend Sabrina and her team enough. Worth double the money. 👏🏻”

Hayley Pearson

“I was lucky enough to first meet Sabrina 9 years ago & have never used anyone else since. She has helped transform my appearance; with natural looking aesthetics. I currently live abroad, however remain dedicated to stay a patient of Sabrina. What’s 3,500 miles when you have found the best in the business!”