Perfect360 Skin - Personalised Skincare

A genetics-led approach to skin health, combining DNA testing, AI skin analysis, and personalised treatment planning with Dr Sabrina and her team.

Perfect360 Skin- Personalised skincare illustration

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The Science

Understanding Healthy Skin Ageing

Your skin's health results from a complex interplay between your genes (your blueprint) and what you are exposed to on a daily basis, and is thus polygenic and multifactorial in nature.

This means that whilst your susceptibility to skin concerns has a strong genetic contribution, many other factors also play a significant role, including environmental exposure to toxins and stress, gut health, hormonal health and age, exercise behaviour, and dietary intake. Therefore, both genes and environment should be considered to better understand the mechanisms behind skin ageing.

The underlying biological mechanisms that have key functions in skin ageing include collagen breakdown and repair (influencing skin elasticity), antioxidant defence and detoxification (influencing skin barrier function and fine wrinkles), DNA repair mechanisms (protecting from UV ageing), melanin production (influencing pigmentation and freckling), moisture retention (influencing barrier function and sensitivity), and sebum production and inflammation (playing a major role in acne and pigmentation).

Watch: Perfect360 Skin
Visia Skin AnalysisPersonalised Medicine and Skincare
The Approach

Personalised Medicine and Skincare

In general, the health of your skin can be measured by considering its appearance through any visual signs of ageing - wrinkles and fine lines, hyper/dyspigmentation, and coarse skin texture. At Perfect Skin Studio we use advanced AI systems like the Canfield Visia Camera to assess external skin ageing that is not easily visible to the naked eye.

Your ethnicity, age, UV exposure, nutrient intake, cosmeceutical use, exposure to environmental pollutants, stress levels, weight management and exercise routine all contribute toward the status of your skin's health.

Within each of these factors, genetics has a major role to play in determining the interindividual variability that exists in the ageing process, as well as your response to environmental input to improve skin health. Our team at Perfect Skin Studio work with Dr Sabrina to recommend precise interventions aimed at helping you reach your goals and achieve optimal skin health.

The Perfect360 Skin Package Includes

Diagram of the biological factors influencing optimal skin health

1. DNA Skin (a pin-prick test)

DNA Skin is a genetic test that offers insight into key areas that influence skin ageing, offering personalised topical, nutraceutical, diet, and lifestyle recommendations for improved outcomes.

DNA Skin reports on your unique genetics - knowledge of your genes and genetic variations offers unparalleled insight into your biological systems, and how the gene variations that you carry could affect your skin and the way it ages.

2. Skin Visia Analysis

Visia accurately detects skin imperfections such as wrinkles, pores, hyperpigmentation, uneven texture, sun damage, bacteria, and oil plugs. The system also compares your skin to the skin of healthy people of similar age, gender, and ethnicity. This helps you understand the condition of your skin and aids you in making treatment choices.

3. Wellness Consultation

A remote 90-minute wellness consult with our Health & Longevity coach Sandie, who will assist in personalising and optimising your lifestyle and diet to enhance your skin health.

4. Doctor Consultation

A remote or in-person consultation with one of the doctors in our team to discuss your unique genetic test results and offer advice and recommendations on oral supplements, a topical skincare regime, and personalised treatment plans for optimising and preventing or reversing the skin ageing changes that you are genetically coded for.

5. Choice of Facial Treatment

A choice of 3D MIRACL UltraClear laser facials (a course of 3 treatments, once a month) to improve the texture of skin - fine lines, wrinkles and hyperpigmentation - versus a course of Endermologie facial detoxifying lymphatic drainage facials (a course of 8 treatments, twice a month) to improve facial puffiness and restore a glow.

A Lifetime of Optimal Skin Health Awaits You

Your genes do not change, which means you will only need one genetic test. However, throughout your life, as your health and lifestyle factors impact your skin health journey, the Perfect Skin Studio and Dr Sabrina's team can continue to provide valuable insights and treatments to optimise your unique skin health.

Dr Sabrina Shah-Desai

Meet the Expert: Dr Sabrina Shah-Desai

Dr Sabrina Shah-Desai is the founder and Medical Director of Perfect Eyes Clinic. With over two decades of surgical and non-surgical experience, she is considered one of the safest, most experienced oculoplastic surgeons in the UK.

Her extensive training, combined with her caring and empathetic nature, makes her a natural choice for patients seeking the very best care. Dr Sabrina appears consistently in Tatlermagazine as one of the UK's “Best Eye Surgeons” and “Top Doctors” since 2019.

Learn About Dr Sabrina
Royal College of Surgeons of England - register of Board-Certified Cosmetic SurgeonsBest Aesthetic Doctor - Safety in Beauty 2023Consultant Surgeon of the YearBest Surgical Result - Aesthetic Awards 2021Tatler Best Eye Surgeon 2019-2026
Transparent pricing

Perfect360 Skin Cost in London

Prices are a guide; your doctor will calculate the total cost during consultation.

  • £1,500 - Skin DNA Test + Consultation with Dr + Online Consultation with our Health & Longevity coach + Visia Skin Scan + Treatments (UltraClear 3D MIRACL Facial or Lymph Drainage)

  • £750 - Skin DNA Test + Online Consultation with our Health & Longevity coach + Visia Skin Scan

  • £600 - Skin DNA Test + Consultation with Dr + Visia Skin Scan

Important: all cosmetic procedures incur 20% VAT. Fees are estimates and will be confirmed after medical consultation.

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Patient stories

Rated five stars by patients across the globe

4.8out of 5 from 240+ Google reviews

Desi StevensRated 5 out of 5 on Google
Simply the best dermatologist for skin care and eye surgery. She is a safe and skilled doctor who is highly experienced and will meet your needs, her approach is a soft and natural aesthetic. She listens and communicates clearly, professionally and in a kind and personable manner. I have been looked after by Dr Sabrina for many years have always been extremely happy with her advice, procedures and results. Highly recommend, she is a talented Dr you can trust.
Kealey HesseyRated 5 out of 5 on Google
Dr Sabrina is the magic eye fairy. Only 10 days after my lower lid bleph and midface lift and nearly all bruising and swelling has gone. After a lot of research, I knew after my initial consultation with Dr Sabrina she was the one I trusted. Such a warm & kind woman. I am so pleased I put my Trust in Dr Shah. Immensely happy with the results and will be back to get my upper eyes done in the future. Thank you to the whole team.
Jo KirbyRated 5 out of 5 on Google
I had been recommended Dr Sabrina by a medical colleague & am extremely glad I made the journey from Southampton to the Perfect Eye Clinic in London to discuss blepharoplasty. The team were all so friendly & very professional and most importantly, Dr Sabrina informed me that I had a bilateral eye ptosis. This explained a number of issues I was experiencing. I will definitely be booking to have a correction of bilateral eye ptosis and upper blepharoplasty. Can't recommend enough.
Shirley FordRated 5 out of 5 on Google
I am so very happy with my experiences at Perfect Eyes. Dr Sabrina is an absolute Star. Extremely talented, very personable I just couldn't be happier with my results and her overall professionalism. But a big part of my review is how lovely the support staff are too. Namely Safiya and Lisa who greet you with such warmness and respect. I highly recommend this clinic as I have done so with many friends.
Radhika RajanRated 5 out of 5 on Google
Top notch surgeon. Dr.Sabrina Shah is the best. Very meticulous and focused. Very experienced and very skillful. Supported by a great team, Irvana at the office is efficient and directs empathy as well towards nervous patients like myself . All in all a great experience.
Tina StonelyRated 5 out of 5 on Google
Dr Sabrina is so so kind and thorough in really assessing and understanding my needs and explaining in detail what works and the pros on cons of each treatment. I trust her implicitly and know she is the best physician in the UK and trainer to physicians for all aesthetic treatments. I cannot recommend her enough. You will not be disappointed choosing Sabrina.
Tanya Del FedericoRated 5 out of 5 on Google
Perfect Eyes provides an exceptional experience from start to finish. The team is warm, professional and highly knowledgeable, and every aspect of the consultation feels thorough and personalised. Sabrina combines outstanding surgical expertise with a genuine commitment to achieving natural, elegant results, taking the time to explain every option and ensure patients feel completely at ease. The care, attention to detail and standard of service are second to none. I would highly recommend Perfect Eyes to anyone looking for expert oculoplastic and aesthetic care.
Minda WangRated 5 out of 5 on Google
I am so happy with my experience. The results look natural, and I feel like a fresher version of myself since having my Biostimulation treatment with Doctor Sabrina. The whole experience was comfortable and professional, and I felt supported and well cared for throughout. I would definitely recommend this treatment to anyone looking for a natural-looking boost.
Samantha AndrewsRated 5 out of 5 on Google
Amazing. I’m so happy with the results. Sabrina is a master. She also has a wonderful bedside manner. I can’t recommend Sabrina and her team enough. Worth double the money. 👏🏻
Hayley PearsonRated 5 out of 5 on Google
I was lucky enough to first meet Sabrina 9 years ago & have never used anyone else since. She has helped transform my appearance; with natural looking aesthetics. I currently live abroad, however remain dedicated to stay a patient of Sabrina. What’s 3,500 miles when you have found the best in the business!

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121 Harley Street, London
Mon to Fri9:30am to 6:00pm
Sat & SunClosed
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Speak to our team about which treatment suits you, or arrange a private consultation at 121 Harley Street.

Call or message020 7183 5121
Opening hoursMon to Fri9:30am to 6:00pmSat & SunClosed
Our locationPerfect Eyes Clinic, 121 Harley Street, London, W1G 6AXGet directions

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