Dark Circles and Polynucleotides or Mesotherapy – by Dr. Sabrina Shah-Desai & her team

What are Polynucleotides or Mesotherapy?

Whilst hyaluronic acid fillers are a standard method of treating the under eye hollows, Polynucleotides are shortened DNA fractions, whilst mesotherapy are injections that contain numerous nutrients and enzymes. Both encourage regenerative changes on a cellular level and are newer alternative to treating loose wrinkly skin & dark circles. The benefits include, increased cell turnover, improved skin elasticity, reduce skin hyperpigmentation, reduced infraorbital hollows due to thin skin, improved fine lines and boosted hyaluronic acid production to give a brighter under eye area.

How does the procedure work?

Dr Sabrina will often use a numbing cream which is applied for 15 mins prior to the procedure. The whole procedure takes around 15 minutes and a fine needle is used to perform the treatment. Polynucleotides (PDRNs), work by signalling to particular cells in the body to change their behaviour and generate collagen, hyaluronic acid and fat. These result in a tighter, brighter, more lifted appearance naturally, but it takes time and a course of treatments.

  • Gradual results – perfect for those seeking a natural subtle improvements
  • Negligible downtime – may be a bit bruised for a few days
  • Unrivalled expertise – performed by leading oculoplastic surgeon and her team

Polynucleotides– Before & After Gallery

Disclaimer: Your results may vary. Any specific claims or length of results vary for each patient and are not guaranteed.

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Patient Questions

Frequently Asked Questions

When will I see results?

Following a course of 2-3 treatments every 3-4 weeks, you can expect to see results

What is the downtime?

There is minimal downtime, however you might experience some bruising, redness or swelling in the treated area. If this happens, it usually subsides within a matter of days, and can be easily covered by makeup.

Is treatment painful?

No as a numbing cream is usually applied beforehand.

How long does the treatment result last?

This is a newer treatment in regenerative aesthetics and currently we believe the treatment needs to be repeated annually.

What are the risks of Polynucleotides/Mesotherapy?

Following treatment an incomplete improvement may occur, if this happens further treatments like under eye hyaluronic acid filler or energy based treatments may be required.

About Dr Sabrina Shah-Desai MS, FRCS

Dr Sabrina Shah-Desai is a distinguished oculoplastic surgeon and one of London’s leading eye specialists. She has over two decades of surgical experience and is renowned for her ability to create a natural look.

Dr Sabrina has a deep anatomical knowledge of the periorbital area and an appreciation for the differences in treating both men and women. When raising the brows and eyelids in a male Upper-Lid Blepharoplasty, it is important to preserve the T-shaped brow – in order not to feminise their appearance.

Tixel Treatment Cost

Prices are a guide; your doctor will calculate total costs during consultation.

Full face & Neck Tixel from £750/ session
Full face, Neck and lower Eyelid Tixel from £950/session
Upper & lower eyelids with brow lift Tixel from £550/session
Lower eyelid & peri-oral lines Tixel from £550/session
Tixel Glow (skin pigmentation) from £550/session

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